Version: 8.0.0
Date: Tue Jan 28 2025
Bmal1tm1Bra
MGI:2180361
Allele of Bmal1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Bmal1tm1Bra

Species
Mus musculus
Symbol
Bmal1tm1Bra
Category
allele
Allele of gene
Bmal1
Transgenic Constructs
None
Synonyms
  • bmal1-
  • Bmal1-KO
Description
A portion of exon 4 containing the helix-loop-helix coding domain and all of exon 5 were replaced by a neomycin selection cassette. A larger transcript, resulting from a cryptic splice site between exon 3 and the neomycin resistance gene, was detected by Northern blot analysis. The polypeptide truncates 15 residues after this splice site, prior to the functional domains encoded by exon 4 in the wild-type locus.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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