Version: 8.0.0
Date: Tue Jan 28 2025
Sim1tm1Fan
MGI:2180390
Allele of Sim1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Sim1tm1Fan

Species
Mus musculus
Symbol
Sim1tm1Fan
Category
allele
Allele of gene
Sim1
Transgenic Constructs
None
Synonyms
  • Sim-
Description
A PGK-neo cassette was inserted to replace the first 750 nucleotides of the 5' region, the initiation codon, and the first 17 codons of the basic helix-loop-helix (bHLH) domain. While message was present in homozygous mutant mice at levels only slightly below normal, immunocytochemistry analysis showed an absence of protein product in the coronal sections of the brain.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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