Bhlhe40^tm1Tan

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Species

Mus musculus

Symbol

Bhlhe40^tm1Tan

Category

allele

Allele of gene

Bhlhe40

Transgenic Constructs

None

Synonyms

• Dec1^-
• S2^-

Show All 3

Description

A neomycin resistance gene under the control of a GTI-II promoter replaced a region encoding the first 6 amino acids, including the initiator-methionine, and a portion of the proximal promoter. Northern blot analyis confirmed a lack of transcript in heart, liver, and kidney tissue obtained from homozygous mutant mice. An absence of protein expression was determined homozygous mutant MEFs via Western blot analysis.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations