Version: 8.0.0
Date: Tue Jan 28 2025
Ctla4tm1Shr
MGI:2180668
Allele of Ctla4
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Ctla4tm1Shr

Species
Mus musculus
Symbol
Ctla4tm1Shr
Category
allele
Allele of gene
Ctla4
Transgenic Constructs
None
Synonyms
  • CTLA-4-
  • Ctla4-
Description
The insertion of a PGK-neo cassette replaced a 1.3 kb region containing exon 2 and a portion of exon 3. The deleted region encoded a IgV and part of a transmembrane domain. Fluorescence-activated cell sorting (FACS) analysis showed an absence of protein in splenocytes isolated from homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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