Cd59a^tm1Bpm

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Species

Mus musculus

Symbol

Cd59a^tm1Bpm

Category

allele

Allele of gene

Cd59a

Transgenic Constructs

None

Synonyms

• CD59^-
• Cd59a-

Show All 3

Description

A neomycin selection cassette was inserted to replace exon 3, which encodes the majority of the protein. FACS analysis showed an absence of protein expression on the surface of erythrocytes, leukocytes, and platelets isolated from homozygous mutant mice. The lack of protein expression was confirmed by immunhistochemical analysis in a variety of tissues.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations