Allele/Variant

Aldh3a1tm1Jpi

Species
Mus musculus
Symbol
Aldh3a1tm1Jpi
Category
allele
Allele of gene
Aldh3a1
Transgenic Constructs
None
Synonyms
  • ALDH3a1-
Description
A PGK-neomycin resistance cassette replaced the 1.2 kb region spanning from within exons 2 to 3 and placed an in-frame translation termination codon immediately after the initiator methionine codon in exon 2, and a putative eukaryotic transcriptional terminator (E. coli tryptophan attenuator) between the inserted stop codon and the neomycin gene. Immunoblot analysis using a rabbit anti-rat antibody did not detect protein in corneal epithelial extracts from homozygous mutant mice. Zymogram analysis of corneal epithelial extracts from homozygous mutant mice did not detect protein activity.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations