Cd9^tm1Kudo

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Species

Mus musculus

Symbol

Cd9^tm1Kudo

Category

allele

Allele of gene

Cd9

Transgenic Constructs

None

Synonyms

• Cd9^-

Description

Exon 2, which encodes the first transmembrane domain, was replaced with a neomycin resistance gene. Sequenc analysis of a transcript present in mutant mice showed that exon 1 had spliced to exon 3 causing a frameshift mutation that introduced a stop codon in exon 3. While a cytoplasmic domain may have been produced, flow cytometric analysis of bone marrow macrophages showed no cell surface protein expression.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations