Kif1c^tm1Noh

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Species

Mus musculus

Symbol

Kif1c^tm1Noh

Category

allele

Allele of gene

Kif1c

Transgenic Constructs

None

Synonyms

• kif1C-

Description

A cassette consisting of a splice acceptor site, an internal ribosomal entry site (IRES), and a lacZ-neomycin resistance gene fusion replaced 2.6 kb of sequence encoding the ATP binding motif P-loop. The cassette was inserted downstream of the ATG-containing exon. A beta-galactosidase fusion protein is expressed from this allele. Immunoblot analysis using a polyclonal antibody against a C-terminal peptide sequence did not detect wild-type protein in brain from homozygous mutant mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations