Allele/Variant

Ccr9tm1.1Mal

Species
Mus musculus
Symbol
Ccr9tm1.1Mal
Category
allele
Allele of gene
Ccr9
Transgenic Constructs
None
Synonyms
  • CCR9-
Description
Mice possessing the Ccr9tm1Mal allele were bred with mice ubiquitously expressing cre-recombinase to generate a locus that lacked exon 3 and the inserted floxed neomycin resistance gene cassette. Both an RT-PCR analysis and an RNase protection assay showed a lack of transcript in homozygous mutant thymus tissue.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal gamma-delta T cell number
MGI
abnormal leukocyte cell numberMGI
abnormal mesenteric lymph node morphology
MGI
abnormal T cell differentiationMGI
abnormal T cell subpopulation ratio
MGI
decreased double-positive T cell numberMGI
decreased gamma-delta intraepithelial T cell number
MGI
decreased pro-B cell numberMGI
decreased T cell numberMGI
increased T cell numberMGI
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Disease Associations