Version: 8.0.0
Date: Tue Jan 28 2025
Cnr2tm1Zim
MGI:2181023
Allele of Cnr2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Cnr2tm1Zim

Species
Mus musculus
Symbol
Cnr2tm1Zim
Category
allele
Allele of gene
Cnr2
Transgenic Constructs
None
Synonyms
  • CB2-
  • CB2tm1
Description
341 nucleotides were deleted from the 3' end of the single exon and replaced with a neomycin selection cassette. The deleted region encoded a portion of the intracellular loop 3, transmembrane domains 6 and 7, and the C-terminus. Absence of ligand-binding in spleen sections and homogenates derived from homozygous mutant mice was determined by receptor autoradiography. In addition, binding studies of brain homogenates confirmed that the brain cannabinoid receptor was unaffected by the targeting event.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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