Allele/Variant

Csf2rbtm1Cgb

Species
Mus musculus
Symbol
Csf2rbtm1Cgb
Category
allele
Allele of gene
Csf2rb
Transgenic Constructs
None
Synonyms
  • Beta-c-
  • Betac-
Description
Exon 7 was disrupted by the insertion of a neomycin selection cassette that introduced stop codons into all three reading frames. A binding assay of homozygous bone marrow cells showed that high affinity binding of the colony stimulating factor was ablated. Binding of interleukin 3 was unaffected in cells isolated from mutant mice, indicating that the homologous interleukin 3 receptor was not affected by the targeting event.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Disease Associations