Allele/Variant

Cd44tm1Mak

Species
Mus musculus
Symbol
Cd44tm1Mak
Category
allele
Allele of gene
Cd44
Transgenic Constructs
None
Synonyms
  • CD44-
Description
The 3' portion of exon 2 and all of exon 3 were replaced by the insertion of a neomycin resistance cassette. The deleted region encodes part of the invariant amino terminus, common to all isoforms. A lack of protein surface expression was observed in spleen, lymph node, and thymus cells via flow cytometry.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations