Allele/Variant

Nodaltm1.2Rob

Species
Mus musculus
Symbol
Nodaltm1.2Rob
Category
allele
Allele of gene
Nodal
Transgenic Constructs
None
Synonyms
  • delta100 nodal.lacZ
  • delta100.lacZ
Description
By homologous recombination in ES cells heterozygous for the Nodaltm1Rob allele, 100 bp of the ASE enhancer region (including the two 10 bp binding sites) was replaced by a loxP-flanked hygromycin selection cassette in cis to the original mutation. Transient expression of Cre recombinase in targeted ES cells resulted in excision of the selection cassette, leaving a single loxP site in place of the enhancer sequences.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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