Version: 8.0.0
Date: Tue Jan 28 2025
Cyp1a1tm1.1Dwn
MGI:2182307
Allele of Cyp1a1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Cyp1a1tm1.1Dwn

Species
Mus musculus
Symbol
Cyp1a1tm1.1Dwn
Category
allele
Allele of gene
Cyp1a1
Transgenic Constructs
None
Synonyms
  • Cyp1a1(-)
Description
Cre recombinase RNA was injected into zygotes heterozygous for Cyp1a1tm1Dwn. A region containing a floxed HPRT minigene and the entire coding region of Cyp1a1 was excised by cre recombinase. Northern and Western blot analyses of total RNA and protein extracts obtained from animals treated with TCDD (to enhance expression levels) showed an absence of endogenous transcript and normal protein in the livers of homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page