Sp3^tm1Sus

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Species

Mus musculus

Symbol

Sp3^tm1Sus

Category

allele

Allele of gene

Sp3

Transgenic Constructs

None

Synonyms

• Sp3-

Description

Exon 2, which encodes the glutamine-rich activation domain, was replaced with a cassette containing an IRES-lacZ-neo fusion gene, adjoined to a splice acceptor site. The three isoforms produced from the endogenous allele were undetected in homozygous mutant mice by Western blot analysis of nuclear extracts.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations