Allele/Variant

Rnaseltm1Slvm

Species
Mus musculus
Symbol
Rnaseltm1Slvm
Category
allele
Allele of gene
Rnasel
Transgenic Constructs
None
Synonyms
  • RL-
  • RNase L-
Description
Exon 1, encoding the activator-binding region, was disrupted at codon 100 by the insertion of a neomycin selection cassette. The absence of normal protein in homozygous mutant mice was determined via Western blot analysis of MEF protein extracts and by binding assays on extracts from various organs. No ribonuclease activity was detected in MEF via Northern blot analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations