Allele/Variant

Nfatc2tm1Srf

Species
Mus musculus
Symbol
Nfatc2tm1Srf
Category
allele
Allele of gene
Nfatc2
Transgenic Constructs
None
Synonyms
  • NF-ATp-
Description
470 base pairs of exon 2 and approximately 400 base pairs of intron 2 were replaced with a neomycin selection cassette. The insertion of the neo gene removed a splice site and introduced stop codons into all three reading frames. Western blot analysis of splenocyte nuclear protein extracts confirmed the absence of normal encoded protein in homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations