Version: 8.0.0
Date: Tue Jan 28 2025
Tg(GFP/KRAS2/ALPP)1Brn
MGI:2182853Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(GFP/KRAS2/ALPP)1Brn

Species
Mus musculus
Symbol
Tg(GFP/KRAS2/ALPP)1Brn
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • G12VKRAS
  • beta-actin::LSL::G12VKRAS
Description
A transgene consisting of a chicken beta actin promoter, followed by a GFP (green fluorescence protein) expression cassette flanked by two lox sites and preceding a human K-RasV12 cDNA combined with an ALPP (PLAP; human placenta-like alkaline phosphatase) expression construct. Expression of oncogenic K-RasV12 is dependent on Cre-mediated deletion of the GFP fragment.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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