Allele/Variant

Slc18a2tm2Kmo

Species
Mus musculus
Symbol
Slc18a2tm2Kmo
Category
allele
Allele of gene
Slc18a2
Transgenic Constructs
None
Synonyms
  • KA1
  • VD-
Description
As a result of incorrect gene targeting, a neomycin resistance cassette inserted between exons 2 and 3 via homologous recombination. A decrease in gene expression in homozygous mutants was observed by RT-PCR analysis of total midbrain RNA using primers to exons 2 and 12. Western blot analysis of striatal membrane extracts from homozygous mutants showed greater than 95% decrease in protein expression compared to wild-type.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page