Allele/Variant

Mtf1tm1Wsc

Species
Mus musculus
Symbol
Mtf1tm1Wsc
Category
allele
Allele of gene
Mtf1
Transgenic Constructs
None
Synonyms
  • MTF-1-
Description
A neomycin selection cassette replaced sequences encoding the first two and a portion of the third zinc-finger domain. RT-PCR analysis of RNA from mutant embryos revealed the presence of an amino-terminal fragment, truncating 39 base pairs downstream of the 5' insertion point. The truncated transcript lacks sequence encoding 3 zinc-finger domains and the acidic, proline-rich, and serine/threonine-rich regions.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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