Gabra2^tm1Uru

---

Species

Mus musculus

Symbol

Gabra2^tm1Uru

Category

allele

Allele of gene

Gabra2

Transgenic Constructs

None

Synonyms

• alpha2(H101R)
• mutant allele 1

Description

A point mutation was introduced into codon 101 (exon 4) resulting in the substitution of histidine with arginine (H101R). The targeting vector also contained a floxed neomycin cassette in intron 3 for selection. Mice carrying this allele were bred with transgenic mice expressing cre recombinase to generate Gabra2^tm1.1Uru.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations