Allele/Variant

Rbp3tm1Gil

Species
Mus musculus
Symbol
Rbp3tm1Gil
Category
allele
Allele of gene
Rbp3
Transgenic Constructs
None
Synonyms
  • IRBP-
Description
Approximately 4.4kb of sequence was replaced by a PGK-neo selection cassette. The deleted region contained the promoter and all but 24 base pairs of exon 1. While transcript was undetected by RT-PCR analysis in homozygous mutant mice, Northern blot analysis of total retinal RNA showed the presence of a truncated transcript containing the PGK-neo transgene and the untargeted exons. Immunocytochemistry showed the absence of protein in homozygous mutant mice. Western blot analysis confirmed the staining results as well as verified the lack of protein produced from the truncated transcript.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations