Version: 8.0.0
Date: Tue Jan 28 2025
Runx3tm1Yg
MGI:2183399
Allele of Runx3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Runx3tm1Yg

Species
Mus musculus
Symbol
Runx3tm1Yg
Category
allele
Allele of gene
Runx3
Transgenic Constructs
None
Synonyms
  • Rehovot-Runx3Lacz
  • Runx3-
Description
Exon 2, encoding the runt domain, was disrupted by the insertion of a cassette containing IRES-lacZ and neo. RT-PCR analysis of dorsal root ganglia RNA extracts showed an absence of transcript in homozygous mutant mice. Protein was undetected by Western blot analysis of thymus tissue and immunostaining of dorsal root ganglia. Expression of beta-galactosidase was visualized in mutant embryos via X-gal staining.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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