Allele/Variant

Icmttm1Hzo

Species
Mus musculus
Symbol
Icmttm1Hzo
Category
allele
Allele of gene
Icmt
Transgenic Constructs
None
Synonyms
  • pccmt-
Description
A floxed region containing exons 2 through 4 was excised via the in vitro expression of cre recombinase. The deleted sequence encoded amino acids 65 through 224. Northern blot analysis of heterozygous mice showed an approximately 50% reduction in transcript levels, whereas transcript was undetected in homozygous mutant embryos by RT-PCR analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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