Version: 8.0.0
Date: Tue Jan 28 2025
Mxd3tm1Rne
MGI:2183621
Allele of Mxd3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Mxd3tm1Rne

Species
Mus musculus
Symbol
Mxd3tm1Rne
Category
allele
Allele of gene
Mxd3
Transgenic Constructs
None
Synonyms
  • mad3-
Description
A neomycin selection cassette replaced a region spanning the start codon in exon 1 and 5.8kb of intronic sequence following exon 4. In addtion to the initial methionine, the deleted sequence encoded the Sin3-interacting domain, a conserved HGYAS motif, and the basic and helix-loop-helix regions of the bHLH leucine zipper. RT-PCR analysis and in situ hybridization confirmed the absence of transcript in homozygous mutant embryos.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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