Allele/Variant

Tg(App)1874Kha

Species
Mus musculus
Symbol
Tg(App)1874Kha
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • moAPPwt
  • Tg(App)1874Kahs
Description
Overexpression of mouse App gene encoding App695.WT (wild-type). The construct contained the App gene fused to the hamster prion protein promoter. App expression was measured in brains of transgenic mice by quantitation of immunoblots. This transgenic line was estimated to contain ~31 copies of the transgene. Other lines generated using this construct varied in copy number and severity of phenoytpe.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations