Allele/Variant

Tg(UcpDta)1Kz

Species
Mus musculus
Symbol
Tg(UcpDta)1Kz
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • BATless
  • UCP-DTA
Description
Incorporation of a toxic transgene, diphtheria toxin-A-chain (Dta), coupled to regulatory elements of the gene for brown adipose tissue specific uncoupling protein (Ucp) resulted in the ablation of brown adipose tissue (BAT). Specifically, Dta was inserted into the first exon of Ucp1 at position +120 to create the vector.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
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