Version: 8.0.0
Date: Tue Jan 28 2025
Lefty2tm2Hmd
MGI:2183818
Allele of Lefty2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Lefty2tm2Hmd

Species
Mus musculus
Symbol
Lefty2tm2Hmd
Category
allele
Allele of gene
Lefty2
Transgenic Constructs
None
Synonyms
  • lefty2deltaASE
  • Rr179tm2Hmd
Description
A 0.5 kb region of the gene containing the asymmetric enhancer (ASE) was replaced with a loxP site flanked neomycin resistance gene cassette via homologous recombination. The floxed neo cassette was subsequently removed by crossing chimeric animals to a cre-expressing line. Ablation of asymmetric gene expression in homozygous mutant embryos was confirmed by whole mount in situ hybridization.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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