Epb41^tm1Cnby

---

Species

Mus musculus

Symbol

Epb41^tm1Cnby

Category

allele

Allele of gene

Epb41

Transgenic Constructs

None

Synonyms

• 4.1^-
• 4.1R^-

Description

Exons 2 through 4 were replaced with a cassette containing beta-galactosidase and neomycin resistance genes. The deleted region contained two start codons encoding high-molecular weight isoforms and 80kD isoforms in exons 2 and 4, respectively. Transcript was undetected by Northern blot analysis using a carboxy terminal coding sequence probe. An 80kD protein was detected in wild-type but not in homozygous mutant mice via Western blot analysis.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations