Ube2b^tm1Jhjh

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Species

Mus musculus

Symbol

Ube2b^tm1Jhjh

Category

allele

Allele of gene

Ube2b

Transgenic Constructs

None

Synonyms

• HR6b-
• mHR6B-

Show All 3

Description

Exon 1 was disrupted by the insertion of a neomycin selection cassette immediately following the start codon. Northern blot analysis showed an absence of transcript in homozygous mutant mice. The absence of protein produced from Ube2b was determined via Western blot analysis of testicular extracts. Further analysis showed that the level of protein produced from the homologous Ube2a locus was unaffected by the targeting event.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations