Allele/Variant

Slc12a7tm1Tjj

Species
Mus musculus
Symbol
Slc12a7tm1Tjj
Category
allele
Allele of gene
Slc12a7
Transgenic Constructs
None
Synonyms
  • Kcc4-/-
Description
Homologous recombination introduced a floxed neo cassette preceding the exon encoding transmembrane span 1 and part of transmembrane span 2 and a third loxP site was introduced after the exon encoding the remainder of transmembrane span 2. The floxed regions were deleted via transient expression of cre recombinase in correctly targeted ES cells. RT-PCR analysis detected a truncated transcript in mutant animals. Western blot analysis did not detect protein product in various tissues from homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations