Allele/Variant

Fdft1tm1Yma

Species
Mus musculus
Symbol
Fdft1tm1Yma
Category
allele
Allele of gene
Fdft1
Transgenic Constructs
None
Synonyms
  • SS-
Description
Exons 4 and 5 were replaced with a neomycin selection cassette. Northern blot analysis of total hepatic RNA from heterozygous mice showed transcript levels to be reduced to 40% of normal. Squalene synthase activity was determined to be reduced by 50% in heterozygous mice via an assay of liver and testis homogenates.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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