Allele/Variant

Hnf1atm1.1Ylee

Species
Mus musculus
Symbol
Hnf1atm1.1Ylee
Category
allele
Allele of gene
Hnf1a
Transgenic Constructs
None
Synonyms
  • Hnf-1alpha-
  • hnf1alpha-
Description
This allele was generated by breeding mice carrying Tcf1tm1Ylee with transgenic mice expressing cre via the EIIa promoter. Cre mediated excision of the floxed fragment, containing the coding region of exon 1 and the neo transgene inserted into intron 1, resulted in the loss of sequence encoding 108 amino acids as well as a portion of intron 1. Transcript was undetected in homozygous mutant mice via RT-PCR analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations