Allele/Variant

Pitx2tm1Rsd

Species
Mus musculus
Symbol
Pitx2tm1Rsd
Category
allele
Allele of gene
Pitx2
Transgenic Constructs
None
Synonyms
  • Pitx2-
  • Pitx2LacZ
Description
The gene was disrupted by replacement of the entire homeodomain and C-terminus with an in-frame lacZ-neo cassette via homologous recombination. Southern blot analysis identified homozygous mutant embryos up to E15. X-gal staining of mutant embryos demonstrated the expression pattern of the lacZ targeted insert is similar to that of endogenous protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations