Allele/Variant

Etv1tm2Tmj

Species
Mus musculus
Symbol
Etv1tm2Tmj
Category
allele
Allele of gene
Etv1
Transgenic Constructs
None
Synonyms
  • Er81nlslacZ
  • Er81NLZ
Description
A cassette containing nls-lacZ was inserted in frame into exon 2. While normal protein was undetected in homozygous mutant embryos at E13.5, approximately 5% of dorsal root ganglion neurons showed reactivity after E15. The authors believe the expression to be that of inactive protein lacking the activation domain.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal axon guidanceMGI
abnormal dorsal root ganglion morphologyMGI
abnormal golgi tendon organ morphologyMGI
abnormal innervation pattern to muscle
MGI
abnormal muscle spindle morphology
MGI
abnormal pacinian corpuscle morphology
MGI
abnormal sensory neuron innervation patternMGI
abnormal ventral spinal root morphology
MGI
absent golgi tendon organ
MGI
ataxia
MGI
Showing 1 - 10 of 16 rows
per page

Disease Associations

No data available