Rb1^tm2Tyj

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Species

Mus musculus

Symbol

Rb1^tm2Tyj

Category

allele

Allele of gene

Rb1

Transgenic Constructs

None

Synonyms

None

Description

Insertion of a hygromycin resistance cassette into one allele of the Rb1 gene replaced part of intron 3 and introduced three nucleotide changes into exon 3, creating two termination codons and a new PstI site. This was accomplished in ES cells in which Rb1 had already been targeted. The resulting ES cells are Rb1^tm1Tyj/Rb1^tm2Tyj.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations