Allele/Variant

Myd88tm1Aki

Species
Mus musculus
Symbol
Myd88tm1Aki
Category
allele
Allele of gene
Myd88
Transgenic Constructs
None
Synonyms
  • MyD88 KO
  • MyD88-
Description
A neomycin selection cassette replaced a 1.0 kb genomic fragment that contained sequences encoding the C-terminal cytoplasmic domain of the protein. Northern blot analysis confirmed that the encoded mRNA could not be detected in the liver and spleen of homozygous mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations