Version: 8.0.0
Date: Tue Jan 28 2025
Hsd17b4tm1Baes
MGI:2385822
Allele of Hsd17b4
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Hsd17b4tm1Baes

Species
Mus musculus
Symbol
Hsd17b4tm1Baes
Category
allele
Allele of gene
Hsd17b4
Transgenic Constructs
None
Synonyms
  • D-PBE-
  • MFP-2-
Description
The gene was disrupted by homologous recombination of exons 1-3 with a neomycin resistance cassette resulting in deletion of the hydratase and dehydrogenase activites of the protein. Absence of gene expression in liver of homozygous mutant animals was demonstrated by Northern and Western blot analysis. Hydratase activity was undetectable in liver homogenates from homozygous mutants.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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