Smarca4^tm1Mag

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Species

Mus musculus

Symbol

Smarca4^tm1Mag

Category

allele

Allele of gene

Smarca4

Transgenic Constructs

None

Synonyms

• Brg1^-
• Brg1^null

Description

A neomycin selection cassette replaced sequence encoding part of the DNA-dependent ATPase domain. The deleted region encoded helicase motif 1, which contains the ATP binding site, and helicase motif 1a. The allele was expected to encode a chimeric protein, though while Northern blot analysis identified transcripts containing both endogenous and neo transgene elements, protein was undetected by Western blot analysis.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations