Allele/Variant

Mmp12tm1Sds

Species
Mus musculus
Symbol
Mmp12tm1Sds
Category
allele
Allele of gene
Mmp12
Transgenic Constructs
None
Synonyms
  • MME-
  • MMP-12-
Description
The gene was disrupted by replacement of the majority of exon 2 with a PGK-neo cassette via homologous recombination. Gene transcription and protein production was absent in homozygous mutant animals as demonstrated by Northern and Western blot analysis of peritoneal macrophages and peritoneal fluid.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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