Allele/Variant

Gdi1tm1Ytk

Species
Mus musculus
Symbol
Gdi1tm1Ytk
Category
allele
Allele of gene
Gdi1
Transgenic Constructs
None
Synonyms
None
Description
2.3 kb of sequence, encompassing exons 3 through 6, were replaced by a neomycin selection cassette inserted via homologous recombination. Western blot analysis of brain extracts showed a lack of protein produced by the targeted allele in homozygous mutant females and hemizygous males.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal excitatory postsynaptic currentsMGI
enhanced paired-pulse facilitationMGI
increased susceptibility to pharmacologically induced seizuresMGI
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Disease Associations

No data available