Version: 8.0.0
Date: Tue Jan 28 2025
Slc6a3tm1Mca
MGI:2386303
Allele of Slc6a3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Slc6a3tm1Mca

Species
Mus musculus
Symbol
Slc6a3tm1Mca
Category
allele
Allele of gene
Slc6a3
Transgenic Constructs
None
Synonyms
  • DAT-
  • DAT-KO
Description
The gene was disrupted by insertion of a neomycin resistance cassette into a coding exon via homologous recombination. Gene expression is absent in the ventral tegmental area (VTA) and dopaminergic cells of the substantia nigra pars compacta (SNC) in homozygous animals as shown by in situ hybridization analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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