Allele/Variant

Wrntm1Lgu

Species
Mus musculus
Symbol
Wrntm1Lgu
Category
allele
Allele of gene
Wrn
Transgenic Constructs
None
Synonyms
  • WRN-
Description
The 3'-most exon encoding part of the catalytic helicase domain was replaced with a beta-geo cassette via homologous recombination. The null allele was confirmed by Western blot analysis of ear fibroblasts derived from homozygous mutant animals. No protein product was detected using antibodies directed against the N- and C-terminal regions of Wrn.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations