Allele/Variant

Cps1tm1Mw

Species
Mus musculus
Symbol
Cps1tm1Mw
Category
allele
Allele of gene
Cps1
Transgenic Constructs
None
Synonyms
  • CPSase (-)
Description
A PGK-neo selection cassette was inserted into exon 17, which encodes an ATP binding domain, via homologous recombination. Enzyme activity was undetected in liver extracts obtained from homozygous mutant mice, indicating a complete functional ablation of the targeted locus. Furthermore, transcript was undetected by RT-PCR analysis of total liver RNA.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations