Lnpep^tm1Ske

---

Species

Mus musculus

Symbol

Lnpep^tm1Ske

Category

allele

Allele of gene

Lnpep

Transgenic Constructs

None

Synonyms

• IRAP^-

Description

Exons 2 through 6 and their intervening introns were replaced with a neomycin resistance gene. The deleted region included sequence encoding the cytoplasmic tail involved in subcellular localization and regulation, the transmembrane domain, and the zinc binding site that is essential for catalytic activity. Western blot analysis indicated an absence of normal protein in homozygous mutant mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations