Version: 8.0.0
Date: Tue Jan 28 2025
Brca2tm1Mbn
MGI:2387337
Allele of Brca2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Brca2tm1Mbn

Species
Mus musculus
Symbol
Brca2tm1Mbn
Category
allele
Allele of gene
Brca2
Transgenic Constructs
None
Synonyms
  • B2-
  • Brca2 delta10/11
Description
Nucleotides 1745 to 2033, encompassing portions of exons 10 and 11 and the intervening intron, were replaced with a neomycin selection cassette. RT-PCR and sequence analyses identified an aberrant transcript containing the first 569 codons of the endogenous gene fused to 75 neo codons. This transcript was undetected by Northern blot analysis, indicating that it was unstable.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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