Version: 8.0.0
Date: Tue Jan 28 2025
G6pc1tm1Jyc
MGI:2387343
Allele of G6pc1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

G6pc1tm1Jyc

Species
Mus musculus
Symbol
G6pc1tm1Jyc
Category
allele
Allele of gene
G6pc1
Transgenic Constructs
None
Synonyms
  • G6Pase-
  • Glc-6-Pase-alpha-
Description
Exon 3 was replaced with a neomycin selection cassette via homologous recombination. Neither transcript nor protein were detected in homozygous mutant mice by a protection assay and Western blot analysis of liver and kidney tissues. Functional ablation was confirmed by the absence of glucose-6-phosphate hydrolysis in liver and kidney microsomes obtained from homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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