Allele/Variant

Prnptm2Edin

Species
Mus musculus
Symbol
Prnptm2Edin
Category
allele
Allele of gene
Prnp
Transgenic Constructs
None
Synonyms
  • mPrP0/0
  • NPU
Description
The gene was disrupted by insertion of a neomycin resistance cassette (under the control of a mouse metallothionein promoter) into exon 3. Northern blot analysis of brain mRNA from homozygous mutant animals did not detect gene transcript, but detected the neo transcript. Western blot of brain membrane fractions from homozygous animals further confirmed the null allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page