Allele/Variant

Cdkn1btm1Jro

Species
Mus musculus
Symbol
Cdkn1btm1Jro
Category
allele
Allele of gene
Cdkn1b
Transgenic Constructs
None
Synonyms
  • p27T187A
Description
The gene was replaced with a construct composed of a loxP-flanked stop box element within the promoter region and a gene carrying a threonine to alanine substitution at position 187 (T187A). The lox-STOP-lox element was removed by breeding homozygous animals to a line expressing cre recombinase constitutively in the germ line thereby allowing expression of the mutant allele in the next generation.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations