Tbx5^tm1.1Jse

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Species

Mus musculus

Symbol

Tbx5^tm1.1Jse

Category

allele

Allele of gene

Tbx5

Transgenic Constructs

None

Synonyms

• Tbx5-
• Tbx5^del

Show All 3

Description

This allele is derived from Tbx5^tm1Jse. The floxed exon 3 and neo cassette were removed by crossing mutant animals to the cre-expressing transgenic line TgN(EIIa-cre)C5379Lmgd. This results in deletion of the N-terminal region of the T-box encoded by exon 3. RT-PCR analysis of mutant animals detected a truncated transcript lacking exon 3.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations